amidophosphoribosyltransferase การใช้

In 1998, Dave Yost suggested that chemists use medial capitals to aid readability of long chemical names, e . g . write AmidoPhosphoRibosylTransferase instead of amidophosphoribosyltransferase.
In 1998, Dave Yost suggested that chemists use medial capitals to aid readability of long chemical names, e . g . write AmidoPhosphoRibosylTransferase instead of amidophosphoribosyltransferase.
Azathioprine's active metabolite methyl-thioinosine monophosphate ( MeTIMP ) is a purine synthesis inhibitor that works by blocking the enzyme amidophosphoribosyltransferase, possibly among others.
The first committed step is the reaction of PRPP, glutamine and water to 5'- phosphoribosylamine ( PRA ), glutamate, and pyrophosphate-catalyzed by amidophosphoribosyltransferase, which is activated by PRPP and inhibited by IMP.
Due to the chemical lability of PRA, which has a half-life of 38 seconds at PH 7.5 and 37 癈, researchers have suggested that the compound is channeled from amidophosphoribosyltransferase to GAR synthetase " in vivo ."