anergic การใช้

Without signal 2, the T cell will not be activated, and will become anergic.
CD28 is the only MHC : antigen complex without CD28 : B7 interaction results in a T cell that is anergic.
This is because B cells need co-stimulatory signals from T cells as well as the presence of its recognized antigen to proliferate and produce anergic.
The second signal comes from co-stimulation, in which surface receptors on the APC are induced by a relatively small number of stimuli, usually products of pathogens, but sometimes breakdown products of cells, such as anergic, and it becomes more difficult for it to activate in future.