carbobenzoxy การใช้

He developed the Bergmann-Zervas carbobenzoxy method for the synthesis of polypeptides.
As a side project, he also worked on applications of Bergmann and Zervas's carbobenzoxy method of peptide synthesis and some of the associated side reactions.
This convinced Bergmann that Curtius'azide degradation could be followed by treatment with benzyl alcohol ( his carbobenzoxy method ) to isolate the resultant amino acid aldehyde and residual peptide amide for sequencing purposes.
The high degree of structural specificity of a broad series of formylated peptides in stimulating these neutrophil responses, the specific binding of N-formylated oligopeptides to neutrophils with affinities that paralleled their stimulating potencies, the ability of " t "-carbobenzoxy-phenylalanyl-methionine to bind to but not stimulate neutrophils and thereby to block the neutrophil binding and stimulating activity of N-formylated oligopeptides, and the ability of the formylated oligopeptides to desensitize ( i . e . render unresponsive ) neutrophil functional responses to themselves but have no or a lesser ability to desensitize to a range of other chemotactic stimuli provided strong suggestive evidence that the formylated peptides acted on cells through a common, dedicated receptor system that differed from other chemotactic factor receptors.