diflunisal การใช้

Effectiveness of diflunisal is similar to other NSAIDs, but the duration of action is twelve hours or more.
Participants were aged 30 to 75 at the outset and were asked about use of NSAIDS including ibuprofen, indomethacin, naproxen and diflunisal.
Collectively, the tafamidis and diflunisal data provide compelling pharmacologic evidence supporting the amyloid hypothesis, the idea that active transthyretin aggregation causes the loss of post-mitotic tissue in this degenerative amyloid disease.
A second statistically significant clinical trial with the repurposed Merck Non steroidal anti-inflammatory drug, diflunisal discovered by Kelly to kinetically stabilize TTR, confirms the validity of the kinetic stabilizer mechanism to ameliorate the TTR amyloidoses.
Numerous other small molecules are known to bind in the thyroxine binding sites, including many natural products ( such as resveratrol ), drugs ( Tafamidis, or Vyndaqel, diflunisal, flufenamic acid ), and toxicants ( PCB ).