enkephalinase การใช้

Various enkephalinase inhibitors, such as ketalorphan, spinorphin, and tynorphin, are mainly exopeptidase inhibitors.
Thiorphan is the active metabolite of racecadotril, which exerts the bulk of its inhibitory actions on enkephalinase.
As such, the analgesic effects of Na v 1.7 blockers may be greatly potentiated by the co-administration of exogenous opioids or enkephalinase inhibitors.
"' Racecadotril "', also known as "'acetorphan "', is an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.
RB-101 is a prodrug which acts by splitting at the disulfide bond once inside the brain, to form two selective enzyme inhibitors and blocking both types of the zinc-metallopeptidase enkephalinase enzymes.