luteinization การใช้

Women who are pregnant sustain the ovarian luteinization process through the production of hCG.
As hCG causes the ovary to undergo extensive luteinization, large amounts of estrogens, progesterone, and local cytokines are released.
This process is called " luteinization ", and the total mass of cells together is called the " corpus luteum ".
In addition, there is evidence that gonadotrophin surge-attenuating factor produced by small follicles during the first half of the follicle phase also exerts a negative feedback on pulsatile luteinizing hormone ( LH ) secretion amplitude, thus allowing a more favorable environment for follicle growth and preventing premature luteinization.
It has been shown that, in mouse KO of " SMAD4 ", the granulosa cells, which secrete hormones and growth factors during the oocyte development, undergo premature luteinization and express lower levels of bone morphogenetic protein-7 effects as BMP-7 uses the SMAD4 signaling pathway.