nonheme การใช้

Heme oxygenase activity is induced by its substrate heme and by various nonheme substances.
A later study found that erythorbic acid is a potent enhancer of nonheme-iron absorption.
Disruption of GLOXY4, encoding a nonheme, ?-ketoglutarate-dependent oxygenase, confirmed its involvement in L-leucine cyclization to form ( 4 " S " )-methyl-L-proline.
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides . 15-LOX-2 has 38-39 % amino acid sequence identity to human 15-LOX-1 and 12-lipoxygenase and 44 % amino acid sequence identity to human 5-lipoxygenase . 15-LOX-2 converts arachidonic acid almost exclusively to the " S " stereoisomer of 15-Hydroperoxyicosatetraenoic acid which is commonly reduced to the " S " stereoisomer 15-Hydroxyeicosatetraenoic acid by ubiquitous cellular peroxidases; it metabolizes linoleic acid less effectively, converting this fatty acid to the " S " stereoisomer of 13-hydroperoxyoctadecadienoic acid which is likewise rapidly reduced to the " S " stereoisomer of 13-Hydroxyoctadecadienoic acid.