nonsecretory การใช้

Patients without evidence of a monoclonal protein may have " nonsecretory " myeloma ( not producing immunoglobulins ); this represents approximately 3 % of all multiple myeloma patients.
The majority of the underlying tumors are " null cell " or nonsecretory tumors, which do not produce excessive amounts of hormones; this might explain why the tumor has often gone undetected prior to an episode of apoplexy.
More recently, serum free light chain assays have been utilised in a number of published studies which have indicated superiority over the urine tests, particularly for patients producing low levels of monoclonal free light chains, as seen in nonsecretory multiple myeloma and AL amyloidosis.
Up to 60 % of PanNETs are nonsecretory or nonfunctional, which either don t secrete, or the quantity or type of products such as pancreatic polypeptide ( PPoma ), chromogranin A, and neurotensin do not cause a clinical syndrome, although blood levels may be elevated.