normoblasts การใช้

He demonstrated the existence of nucleated red blood cells, which he subdivided into normoblasts, megaloblasts, microblasts and poikiloblasts; he had discovered the precursors of erythrocytes.
It is minimally expressed in the primitive and fetal definitive erythroid cells, but is highly expressed in adult definitive erythroid cells, particularly in the proerythroblast and the orthochromatic normoblasts.
Also topographic alteration of the nucleated erythroid cells can be seen in early myelodysplasia ( RA and RARS ), where normoblasts are seen next to bony trabeculae instead of forming normal interstitially placed erythroid islands.
Nucleated red blood cells in mammals consist of two forms : normoblasts, which are normal erythropoietic precursors to mature red blood cells, and megaloblasts, which are abnormally large precursors that occur in megaloblastic anemias.