oncovin การใช้

Oncovin, more commonly known as vincristine, is a mitotic inhibitor.
Vincristine was approved by the United States Food and Drug Administration ( FDA ) in July 1963 as Oncovin.
For example, the CHOP regimen consists of cyclophosphamide, hydroxydaunorubicin ( doxorubicin ), vincristine ( Oncovin ), and prednisone.
Although this drug still cannot strictly target cancer cells, cancer cells have a higher average turnover of microtubules making them more susceptible to the cytotoxicity of oncovin.
The treatment that the three doctors developed and tested, commonly called MOPP _ for the four drugs mustargen, oncovin, procarbazine and prednisone _ had kept about 70 percent of patients alive and free of Hodgkin's disease five years after diagnosis.