picrotoxin การใช้

The protein also contains a number of different inhaled anaesthetics, and picrotoxin, among others.
It is also toxic to mice and dogs, producing convulsant effects that are similar to those of picrotoxin.
On the other hand, evidence exists that picrotoxin acts as a competitive antagonist, and not as a channel blocker.
Strychnine is subcategorized as a convulsant along with picrotoxin and bicuculline, thought these convulsant inhibit GABA receptors instead of glycine.
This could, for example, mean that picrotoxin enhances the occurrence of a desensitized state or an allosterically blocked state ."