tfiiib การใช้
ประโยค
- TFIIIB150 is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription.
- This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB ( TFIIIB ).
- Recently, FUS / TLS was also shown to repress the transcription of RNAP III genes and to co-immunoprecipitate with TBP and the TFIIIB complex.
- The conserved domains of MTA1 include a BAH ( Bromo-Adjacent Homology ), a ELM2 ( egl-27 and MTA1 homology ), a SANT ( SWI, ADA2, N-CoR, TFIIIB-B ) and a GATA-like zinc finger.
- The overall organization of MTA3 protein domains is similar to the other two family members with a BAH ( Bromo-Adjacent Homology ), a ELM2 ( egl-27 and MTA1 homology ), a SANT ( SWI, ADA2, N-CoR, TFIIIB-B ), a GATA-like zinc finger, and one predicted bipartite nuclear localization signal ( NLS ).