thalassemic การใช้

Thalassemic erythrocytes adhere to parasitized red cells much less readily than do their normal counterparts.
The other forms of the disease require a pre-existing medical condition, usually associated with thalassemic hemoglobinopathy.
The serial analyses of ?-thalassemic mice indicate hemoglobin levels decreases over time, while the concentration of iron in the liver, spleen, and kidneys markedly increases.
Increasing expression of hepcidin in ?-thalassemic mice limits iron overload, and also decreases formation of insoluble membrane-bound globins and reactive oxygen species, and improves anemia.
This reaction is experienced by thalassemic RBCs to a greater extent because, not only are there more oxidative radicals in thalassemic blood, but thalassemic RBCs also have limited antioxidant defense.