thiosemicarbazone การใช้

"' Acetone thiosemicarbazone "'is a chemical compound with the molecular formula C 4 H 9 N 3 S . It is used in the plastics industry in the manufacture of polyvinyl chloride ( PVC ) to terminate the polymerization process.
Dr . Sartorelli has a long-standing interest in ribonucleotide reductase inhibitors as anticancer agents, and in collaboration with the late Dr . Tai-Shun Lin, and Dr . Mao-Chin Liu, a large number of thiosemicarbazone based ribonucleotide reductase inhibitors were synthesized over several decades . 3AP was chosen, based on the results of studying and the screening these products, as the candidate inhibitor most likely to express activity in the setting of human neoplastic disease ., 3AP is being developed by Vion Pharmaceuticals.