tyrosinemias การใช้

Tyrosinemia is the most common metabolic disease associated with tyrosine aminotransferase.
The drug, named Orfadin, amazingly is a failed weed killer that Swedish scientists discovered could fight a disease called hereditary tyrosinemia.
Hereditary tyrosinemia type 1, or HT-1, is a genetic metabolic disorder that causes progressive liver failure and liver cancer in young children.
In Type I tyrosinemia, a different enzyme, fumarylacetoacetate hydrolase is mutated and doesn't work, leading to very harmful products building up in the body.
Tyrosinemia type II ( Richner-Hanhart syndrome, RHS ) is a disease of autosomal recessive inheritance characterized by keratitis, palmoplantar hyperkeratosis, mental retardation, and elevated blood tyrosine levels.