corneal endothelium การใช้

• The corneal endothelium are specialized, flattened, mitochondria-rich eye.
• Patients with CES suffer from compromised corneal endothelium resulting from chronic hypoxia and acidosis.
• During surgery the patient's corneal endothelium is removed and replaced with donor tissue.
• His PhD thesis on corneal permeability introduced the pump-leak hypothesis for the corneal endothelium.
• The normal corneal endothelium is a single layer of uniformly sized cells with a predominantly hexagonal shape.
• Posterior to the stroma is Descemet's membrane, which is a basement membrane for the corneal endothelium.
• More recently, new corneal transplant techniques have been developed to enable more selective replacement of the diseased corneal endothelium.
• This approach, termed endokeratoplasty, is most appropriate for disease processes that exclusively or predominantly involve the corneal endothelium.
• The clinical course of this condition suggests that Calotropis is paradoxically relatively nontoxic to corneal epithelium and highly toxic to corneal endothelium.
• When the Sato procedure was developed, there was no awareness of the importance of a layer of eye cells known as the corneal endothelium.
• The corneal endothelium is attached to the rest of the cornea through Descemet's membrane, which is an acellular layer composed mostly of collagen.
• Some evidence suggests that the corneal endothelium actually possesses stem cells that can produce endothelial cells, especially after injury, albeit on a limited scale.
• Penetrating keratoplasty is preferred when the disease process involves irreversible damage not just to the corneal endothelium, but to other layers of the cornea as well.
• Collectively, these symptoms constitute Corneal Exhaustion Syndrom ( CES ), which is associated with corneal endothelium abnormalities including edema, polymegethism, irregular mosaic, and pigment deposition.
• The corneal endothelium governs fluid and solute transport across the posterior surface of the cornea and actively maintains the cornea in the slightly dehydrated state that is required for optical transparency.
• By making incisions into both the front and back of the eye during the Sato procedure, surgeons were unknowingly disrupting the corneal endothelium, which would lead to corneal complications years later.
• -- > It manifests as severe corneal opacification or clouding, sometimes congenital, in the form of a ground glass, milky corneal tissue, and moon crater-like changes of corneal endothelium.
• Although there is some permanent damage to the corneal endothelium with decreased endothelial cell count and irregular shape, the remaining corneal endothelial cells usually recover with complete resolution of the corneal edema and a return to normal visual acuity.
• Vogt was a pioneer of specular microscopy; around 1913 he used a slit lamp together with a corneal microscope to investigate the structures of the anterior areas of the eye, and in 1918 he was the first to perform direct examination of the corneal endothelium.
• Yu-Mei Diao, Jing Hong, Rong-mei Peng, Meng Chen, and Mark Tso, Feasibility and Safety of Procine Corneal Descemet s Membranes as a Carrier for Tissue Engineered Corneal Endothelium, Molecular Medicine Reports, 2014 December, 12 : 1929-1934