ecl cells การใช้

• The most important inhibitor of the ECL cell is somatostatin from oxyntic D cells.
• The hydrogen potassium ATPase is activated indirectly by gastrin that causes ECL cells to release histamine.
• Gastrin stimulates acid secretion by directly stimulating parietal cells as well as by promoting histamine secretion by ECL cells.
• However, ECL cells are activated directly by ACh on M1 receptors from direct vagal innervation leading to histamine release.
• Gastrin is transferred from a specific type of G cell in the gastric epithelium to the ECL cells by blood.
• Two, the ECL cells of the lamina propria of the body of the stomach are stimulated to release histamine.
• 2 . ) In the lamina propria of the body of the stomach the ACh released from the vagal endings triggers histamine secretion from ECL cells.
• Gastrin primarily induces acid-secretion indirectly, increasing histamine synthesis in ECL cells, which in turn signal parietal cells via histamine release / H2 stimulation.
• Gastrin exerts a trophic effect on enterochromaffin-like cells ( ECL cells are responsible for histamine secretion ) and is hypothesized to be one mechanism to explain the malignant transformation of ECL cells into carcinoid tumors in AMAG.
• Gastrin exerts a trophic effect on enterochromaffin-like cells ( ECL cells are responsible for histamine secretion ) and is hypothesized to be one mechanism to explain the malignant transformation of ECL cells into carcinoid tumors in AMAG.
• This is done both directly on the parietal cell and indirectly via binding onto CCK2 / gastrin receptors on ECL cells in the stomach, which then responds by releasing histamine, which in turn acts in a paracrine manner on parietal cells stimulating them to secrete H + ions.