isosteric การใช้

*Procainamide, an amide, has a longer duration of action than Procaine, an ester, because of the isosteric replacement of the ester oxygen with a nitrogen atom.
First, in the case of the diaryl system "'9 "', relatively high stereoselectively is achieved despite the isosteric nature of the ketone substituents, suggesting that electronics in addition to sterics may play a role in the stereoselectivity of the CBS reduction.
One approach is the design of soft drugs ( SDs ), new, active therapeutic agents, often isosteric or isolelectronic analogs of a lead compound, with a chemical structure specifically designed to allow predictable metabolism into inactive metabolites after exerting their desired therapeutic effect ( s ).