transpeptidases การใช้

PBPs, also known as transpeptidases, are targets for beta-lactams.
They interact with murein synthases as well as two transpeptidases ( PBP2 and PBP3 ).
The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by DD-transpeptidases which are penicillin binding proteins ( PBPs ).
Transpeptidases, such as the sortases responsible for anchoring factors like protein A to the staphylococcal peptidoglycan, are being studied in hopes of developing new antibiotics to target MRSA infections.
The " mecA " gene does not allow the ringlike structure of penicillin-like antibiotics to bind to the enzymes that help form the cell wall of the bacterium ( transpeptidases ), and hence the bacteria is able to replicate as normal.