acrania การใช้

• Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.
• Disruption of these pathways leads to abnormal bone and cartilage formation causing acrania and multiple other craniofacial patterning problems.
• Recent work has identified mutations in the hedgehog acyltransferase ( HHAT ) gene that have caused acrania along with holoprosencephaly and agnathia.
• Also, it has been found that mice homozygous for deficiency in the Cart1 gene manifested acrania and meroanencephaly, and prenatal treatment with folic acid will suppress acrania and meroanencephaly in the Cart1-deficient mutants.
• Also, it has been found that mice homozygous for deficiency in the Cart1 gene manifested acrania and meroanencephaly, and prenatal treatment with folic acid will suppress acrania and meroanencephaly in the Cart1-deficient mutants.