ampa การใช้

• All AMPA receptors occur in flip and flop alternatively spliced variants.
• AMPA receptor activation is key for ischemic-induced cell death.
• Glutamate activates NMDA and AMPA receptors which produce action potentials.
• Oxiracetam acts also as a positive allosteric modulator of the AMPA receptors.
• It has been investigated for its effect on AMPA receptors.
• AMPA receptors are also involved in benzodiazepine tolerance and withdrawal.
• SGK mRNA expression in the hippocampus in enhanced by the AMPA receptor.
• AMPA generates fast excitatory postsynaptic potentials ( EPSP ).
• AMPA receptors ), improving cation conduction, and thereby potentiating the synapse.
• To test this hypothesis, researchers administered AMPA antagonist drugs into affected mice.
• The AMPA receptors are ionotropic receptors that are responsible for fast synaptic transmission.
• The intracellular buildup of glutamate triggers the overstimulation of AMPA and NMDA receptors.
• AMPA and Kainate receptors are regulated by SGK isoforms.
• The primary auditory cortex is subject to glutamatergic excitatory postsynaptic potentials at AMPA receptors.
• The NG 2 glial cells express AMPA receptors.
• AMPA receptors that occur in the Flop form desenstise faster than the flip form.
• Like other AMPA receptor antagonists, GYKI-52466 has anticonvulsant and neuroprotective properties.
• Another GFP antibody was then used to label the GluR2 subunit of AMPA receptors.
• This form of AMPA receptor trafficking is hypothesized to be directed by local mRNA transcription.
• Conversely, GRIP-1b increases intracellular levels of AMPA receptors under the same conditions.