androstane การใช้

• It is the 5?-isomer of androstane.
• Androstenol, along with several isomers of androstanol, is an antagonist of the constitutive androstane receptor ( CAR ).
• In similar manner, the estrogens possess an estrane skeleton ( C18 ), and androgens, an androstane skeleton ( C19 ).
• The gene expression of these isoenzymes is regulated by human pregnane receptor X ( PXR ) and constitutive androstane receptor ( CAR ).
• More recently, dehydroepiandrosterone ( DHEA ), also an androstane, has been found to be an endogenous agonist of the CAR.
• DHT is a 5?-androstane ( C19 ) steroid with a ketone group at the C3 position and a hydroxyl group at the C17? position.
• The constitutive androstane receptor, pregnane X receptor and nuclear factor ( erythroid-derived 2 )-like 2 ( Nrf2 ) transcription factors are involved in mediating induction.
• They are distinguished as 5?-androstanedione ( 5?-androstane-3, 17-dione ) and 5?-androstanedione ( 5?-androstane-3, 17-dione ).
• They are distinguished as 5?-androstanedione ( 5?-androstane-3, 17-dione ) and 5?-androstanedione ( 5?-androstane-3, 17-dione ).
• In the days after the fight, it was revealed that Silva tested positive for Drostanolone and Androstane, two anabolic steroids, in pre-fight drug screening on January 9, 2015.
• This enzyme acts on the 3alpha-hydroxy group of androgens of the 5alpha-androstane series; and also, more slowly, on the 17alpha-hydroxy group of both androgenic and estrogenic substrates ( cf.
• An orally active synthetic analogue of 3?-androstanediol, 17?-ethynyl-5?-androstane-3?, 17?-diol ( HE-3235, Apoptone ), was formerly under investigation for the treatment of prostate cancer and breast cancer.
• Estrane ( C18 ) is the 13?-methyl variant of gonane, androstane ( C19 ) is the 10?, 13?-dimethyl variant of gonane, and pregnane ( C21 ) is the 10?, 13?-dimethyl, 17?-ethyl variant of gonane.