anticholinesterases การใช้

• Elkes graduated in 1941 and was invited by Frazer to join him as a research fellow in pharmacology at anticholinesterases and the action of acetylcholine.
• As with all clinically established ( as well as experimental agents ) with a non-depolarizing mechanism of action, its pharmacological action can be antagonized by anticholinesterases.
• Outside of biochemical warfare, anticholinesterases are also used for reversing medication induced paralysis during anesthesia; as well as in the treatment of myasthenia gravis, glaucoma, and Alzheimer's disease.
• Symptoms of envenomation can be reversed through the use of death adder antivenom, or using anticholinesterases, which break the synaptic blockade by making acetylcholine more available to the parasympathetic nervous system, thus mitigating the effects of the venom.
• The following precautions should be kept in mind in the treatment of anticholinesterase poisoning, although they do not bear directly on the use of pralidoxime : since barbiturates are potentiated by the anticholinesterases, they should be used cautiously in the treatment of convulsions; morphine, theophylline, aminophylline, succinylcholine, reserpine, and phenothiazine-type tranquilizers should be avoided in patients with organophosphate poisoning.