apoe การใช้

• ApoE, for example, is a copper-binding protein.
• A small amount of apoE also is in the bone marrow.
• ApoER2 interaction with reelin and ApoE has implications with Alzheimer s disease.
• This is the third or fourth gene associated in combination with APOE 4.
• APOE is the principal cholesterol carrier in the brain.
• APOE was initially recognized for its importance in lipoprotein metabolism and cardiovascular disease.
• ApoE competes with reelin in binding to ApoER2 resulting in weakened reelin signaling.
• Those with ApoE 2, on the other hand, have a low risk.
• APOE is one of a series of genes that is involved in cell repair.
• Apolipoprotein E ( ApoE ) plays an important role in phospholipid and cholesterol homeostasis.
• The normal ApoE turns into the defective ApoE2 form due to a genetic mutation.
• The new findings about ApoE makes this look like it might be a realistic goal.
• The ApoE 3 genotype confers average risk.
• Exchangeable apolipoproteins ( apoA, apoC and apoE ) have the same gene cluster on chromosome 11.
• A role for the " ApoE " gene was initially suspected but could not be confirmed.
• The multiple copies of ApoE allow IDL to bind to the LDL receptor with a very high affinity.
• ApoE may be the signalling ligand responsible for ApoER2's role in modulating the JNK signalling pathway.
• When IDL is converted to LDL, the ApoE leaves the particle and only the ApoB-100 remains.
• Cholesterol is imported into the neuron by apolipoprotein E ( apoE ) via LRP1 receptors on the cell surface.
• Everyone has two copies of the ApoE gene, which comes in three varieties _ 2, 3 and 4.