azole การใช้

• Erg11 / Cyp51 is the target of the azole antifungal drugs.
• The topically applied azole drugs are more effective than nystatin.
• It has a relatively broad spectrum compared to azole compounds but not triazole compounds.
• Other studies employ spectrophotometry to quantify azole-CYP51 interactions ( Becher et al . ).
• The particulate copper systems provide a lighter color than dissolved copper systems such as ACQ or copper azole.
• Type C copper azole, denoted as CA-C, has been introduced under the Wolmanized brand.
• The general appearance of wood treated with copper azole preservative is similar to CCA with a green colouration.
• The commonly used azole class antifungal drugs work by inhibition of the fungal cytochrome P450 14?-demethylase.
• Development of resistance to one azole in this way will confer resistance to all drugs in the class.
• "' Isoconazole "'is an azole antifungal drug and could inhibit gram positive bacteria.
• As with cyanobactins and LAPs, azole and azoline synthesis occurs via the action of an domain cyclodehydratase.
• The indoxyl that is liberated combines with a diazonium salt in order to produce a violet coloured azole dye.
• Antifungal treatment is the regular course of treatment, typically the AZOLE family is used ( i . e Miconazole ).
• These mutations prevent the azole drug from binding, while still allowing binding of the enzyme's natural substrate, lanosterol.
• Most are considerably shorter, between 1000 and 3000 words; at the low end, Azole is a mere 165 words.
• In very severe cases, combination therapy with amphotericin B and an azole have been postulated, although no trials have been conducted.
• It differs from earlier azole antifungals ( such as ketoconazole ) in that its structure contains a triazole ring instead of an imidazole ring.
• Though rare, there have been cases of serious hepatic reactions during treatment with voriconazole ( a class effect of azole antifungal agents ).
• The effectiveness of imidazoles and triazoles ( common azole subclasses ) as inhibitors of 14 ?-demethylase have been confirmed through several experiments.