benzilate การใช้

• Experts also mentioned BZ, or 3-quinuclidinyl benzilate, as a possibility for the gas used by the Russians.
• Officially called 3-Quinuclidinyl Benzilate, BZ is a nerve agent similar to the drug LSD which produces hallucinations in victims.
• Both the N-methyl and N-ethyl analogues of 3-piperidyl benzilate are, however, Schedule I controlled drugs.
• It is used in manufacture of the incapacitating agent 3-quinuclidinyl benzilate ( BZ ) and is regulated by the Chemical Weapons Convention.
• By contrast, the nerve agent BZ, whose chemical name is 3-quinuclidinyl benzilate, is totally banned by the Chemical Weapons Convention.
• The use of 3-Quinuclidinyl benzilate or Agent BZ was alleged in Operation White Wing by journalist Pierre Darcourt in " L'Express " news magazine.
• One of the anticholinergic compounds, 3-quinuclidinyl benzilate, was assigned the NATO code BZ and was weaponized at the beginning of the 1960s for possible battlefield use.
• The ditran mixture is more potent as an anticholinergic than the piperidyl benzilate drugs such as N-methyl-3-piperidyl benzilate, but is less potent than QNB.
• The ditran mixture is more potent as an anticholinergic than the piperidyl benzilate drugs such as N-methyl-3-piperidyl benzilate, but is less potent than QNB.
• However they were disadvantaged by producing severe hypotension at incapacitating doses, and were not as effective as the more widely publicised anticholinergic agents such as 3-Quinuclidinyl benzilate which had also already been weaponised.
• There has been a modest amount of scientific research using this mixture, but most modern research using these kind of anticholinergic drugs uses N-methyl-3-piperidyl benzilate due to its wider availability.
• Alastair Hay, a lecturer in chemical pathology at the University of Leeds, said such irrational behavior is typical of people exposed to the hallucinogenic chemical BZ, which is officially known as 3-Quinuclidinyl Benzilate.
• The U . S . began stockpile reductions in the 1980s with the removal of outdated munitions and destroying its entire stock of 3-Quinuclidinyl benzilate ( BZ or Agent 15 ) at the beginning of 1988.
• "N "-methyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects.
• "N "-methyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects.
• "N "-Ethyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects.
• "N "-Ethyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects.
• "' Benzilylcholine mustard "'( " N "-2-chloroethyl-" N "-methyl 2-aminoethyl benzilate ) is a modified version of acetylcholine, so named because after cyclization in solution it forms an receptor occupancy and response.
• Sedatives or hypnotics that alter higher cognitive function include ethanol, scopolamine, 3-quinuclidinyl benzilate, potent short or intermediate acting hypnotic benzodiazepines such as midazolam, flunitrazepam, and various short and ultra-short acting barbiturates including sodium thiopental ( commonly known by the brand name Sodium Pentothal ) and amobarbital ( formerly known as sodium amytal ).
• These workers also reported that MLA displaced 125 I-?-bungarotoxin from purified " Torpedo " ( electric ray ) nicotinic acetylcholine receptors ( nAChRs ) with a K i ~ 1 x 10  " 6 M . Similar experiments performed later by Ward et al . showed that MLA bound to nAChRs extracted from human muscle with a K i of ~ 8 x 10  " 6 M; it was also reported that MLA, at a concentration of 10  " 4 M, had no affinity for muscarinic AChRs, as labeled by tritiated quinuclidinyl benzilate, from rat brain.