bisphosphonates การใช้

• The two types of bisphosphonates work differently in killing osteoclast cells.
• Bisphosphonates appear to work by blocking these signals, thus reducing metastases.
• Nobody knows about the long-term safety of bisphosphonates,
• Etidronate, unlike other bisphosphonates, also prevents bone calcification.
• Bisphosphonates are already used to fight osteoporosis in women who cannot take estrogen.
• Some people with severe osteoporosis might be prescribed bisphosphonates.
• Bisphosphonates are beneficial in reducing the risk of vertebral fracture in steroid induced osteoporosis.
• Aredia, one of a class of compounds called bisphosphonates, did not increase survival.
• Bisphosphonates can also reduce mortality in those with multiple myeloma, breast and prostate cancer.
• For this reason, other bisphosphonates, like alendronate, are preferred when fighting osteoporosis.
• However, in patients on bisphosphonates, the cortical bone is frequently involved as well.
• Alendronate belongs to a class of drugs called bisphosphonates, which prevent bone from breaking down.
• But he noted other studies that showed drugs called bisphosphonates were effective in countering bone loss.
• In postmenopausal women, the selective estrogen receptor modulator raloxifene is occasionally administered instead of bisphosphonates.
• In patients with bisphosphonates-associated ONJ, the response to surgical treatment is usually poor.
• The inflammatory response to bisphosphonates or fluctuations in calcium blood levels have been suggested as possible mechanisms.
• The drug, sold by Novartis Pharmaceuticals Corp . as Zometa, is in a class called bisphosphonates.
• Bisphosphonates that contain isoprene chains at the R1 or R2 position can impart specificity for inhibition of GGPS1.
• Some studies have found oral and intravenous bisphosphonates, such as oral alendronate and intravenous pamidronate, equivalent.
• Alendronate is the first in a class of drugs known as bisphosphonates that work directly on bone without hormones.