bromouracil การใช้
- TDG can also remove uracil and 5-bromouracil from mispairings with guanine.
- One of the most common base analogs is 5-bromouracil ( 5BU ), the abnormal base found in the mutagenic nucleotide analog BrdU . When a nucleotide containing 5-bromouracil is incorporated into the DNA, it is most likely to pair with adenine; however, it can spontaneously shift into another isomer which pairs with a different nucleobase, guanine.
- One of the most common base analogs is 5-bromouracil ( 5BU ), the abnormal base found in the mutagenic nucleotide analog BrdU . When a nucleotide containing 5-bromouracil is incorporated into the DNA, it is most likely to pair with adenine; however, it can spontaneously shift into another isomer which pairs with a different nucleobase, guanine.