calpain การใช้

• Consequently there is a release of calcium ions that activate calpain.
• This gene encodes the large subunit of the ubiquitous enzyme, calpain 2.
• Calpain cleaves aggregin, and thus allows for joining of the two subunits.
• This gene encodes the large subunit of the ubiquitous enzyme, calpain 1.
• Absence of FOXJ1 expression decreases calpastatin, an inhibitor of the protease calpain.
• Calpain dysregulation affects basal body anchoring to the apical cytoskeleton affecting axeonemal formation.
• The gene tells the body how to make a protein called calpain-10.
• Like other genes, the calpain-10 gene comes in subtly different forms.
• Calpain cleavage may indicate activation of necrosis, while caspase cleavage may indicate apoptosis.
• Myc cleavage is mediated by the calpain family of calcium-dependent cytosolic proteases.
• To date, these two isoforms remain the best characterised members of the calpain family.
• The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits.
• The gene has been named calpain-10 after a family of known genes it resembles.
• Calpain-10 and other genes involved in its pathway may provide new targets for drugs.
• The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form.
• Some suggest the longevity in bats is related to the calpain content of neurons ( Fenton ).
• NNK activates ?en m-calpain kinase which induce lung metastasis via the ERK1 / 2 pathway.
• Enhanced calpain activity, regulated by CAPNS1, significantly contributes to platelet reactivity and thrombosis under hypoxic conditions.
• However, calpain may also be involved in a " resculpting " process that helps repair damage after injury.
• This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin.