camphoric การใช้

• Haller and Blanc published a semisynthesis of camphor from camphoric acid.
• Methylation with methyl iodide and a complicated reduction procedure produced camphoric acid.
• Camphoric acid, however, had an unknown structure.
• Haller and Blanc synthesized camphor from camphoric acid.
• The first complete total synthesis of camphoric acid was published by Gustaf Komppa in 1903.
• In the 19th century, it was known that nitric acid oxidizes camphor into camphoric acid.
• In 1904, Finnish chemist Gustav Komppa became the first to succeed in manufacturing synthetic camphoric acid from diethyl oxalate and 3, 3-dimethylpentanoic acid.
• "' Camphoric acid "', "'Latin form "'Acidum camphoricum "', is a white crystallisable substance obtained from the oxidation of camphor, it exists in three optically different forms; dextrorotatory one is obtained by the oxidation of dextrorotatory camphor and used in pharmaceuticals.