catecholaminergic การใช้

• Congenital problems include long QT syndrome and catecholaminergic polymorphic ventricular tachycardia.
• Amphetamine and methamphetamine are indirect agonists of the catecholaminergic systems.
• Tyrosine is a highly concentrated amino acid in catecholaminergic neurons
• A mode of inheritance is currently unknown, but it is most probably polygenic . dopaminergic and catecholaminergic systems.
• Because serotonin and the related hormone melatonin are involved in promoting sleep, they counterbalance the wake-promoting action of increased catecholaminergic neurotransmission.
• It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of noradrenergic phenotype.
• Mutations in the " RYR2 " gene are associated with catecholaminergic polymorphic ventricular tachycardia, stress-induced polymorphic ventricular tachycardia, and arrhythmogenic right ventricular dysplasia.
• Causes of SADS in young people include viral myocarditis, long QT syndrome, Brugada syndrome, Catecholaminergic polymorphic ventricular tachycardia, hypertrophic cardiomyopathy and arrhythmogenic right ventricular dysplasia.
• The RVLM is a primary regulator of the sympathetic nervous system; it sends catecholaminergic projections to the sympathetic preganglionic neurons in the intermediolateral nucleus of the spinal cord via reticulospinal tract.
• It can be used in the treatment of cardiac arrhythmias, heart failure, catecholaminergic polymorphic ventricular tachycardia ( CPVT ) and store overload-induced Ca 2 + release ( SOICR ).
• A "'catecholaminergic agent "'( or "'drug "') is a chemical which functions to directly modulate the catecholamine systems in the body or brain.
• While Flecainide therapy has been shown to suppress ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia ( CPVT ) and mouse models of this disease, the relative contribution from the inhibition of sodium channels and of RyR2 in this effect on CPVT is unclear.
• Rare diseases called channelopathies may play a roles such as long QT syndrome ( LQTS ), Brugada syndrome CPVT ( catecholaminergic polymorphic ventricular tachycardia ), PCCD ( progressive cardiac conduction defect ), early repolarisation syndrome, mixed sodium channel disease, and short QT syndrome.
• Electroencephalography ( EEG ) studies of animals suggest that adapromine and related adamantanes including amantadine, bromantane ( 1-amino-2-bromophenyladamantane ), and memantine have psychostimulant-like and possibly antidepressant-like effects, and that these effects may be mediated via catecholaminergic processes.
• In comparison to MDMA, it has approximately 3x lower dose, has more balanced catecholaminergic effects relative to serotonergic, and behaves more like a reuptake inhibitor like methylphenidate than a releaser like amphetamine; however, methylone has relatively robust releasing capabilities, perhaps due to its ability to phosphorylate the monoamine transporters being similar in potency relative to MDMA.
• Recently ( 2008 ), it was shown that the conditional deletion of " Mecp2 " in catecholaminergic neurons ( by crossing of Th-Cre mice with loxP-flanked " Mecp2 " ones ) recapitulates a motor symptomatology, it was further documented that brain levels of Th in mice lacking " MeCP2 " in catecholaminergic neurons only are reduced, participating to the motor phenotype.
• Recently ( 2008 ), it was shown that the conditional deletion of " Mecp2 " in catecholaminergic neurons ( by crossing of Th-Cre mice with loxP-flanked " Mecp2 " ones ) recapitulates a motor symptomatology, it was further documented that brain levels of Th in mice lacking " MeCP2 " in catecholaminergic neurons only are reduced, participating to the motor phenotype.