centimorgan การใช้

• The typical unit of genetic linkage is the centimorgan ( cM ).
• In the Human genome, the centimorgan is about 1 million base pairs.
• One centimorgan corresponds to about 1 million base pairs in humans on average.
• The centimorgan, which expresses the frequency of crossing over, is named in his honour.
• :Centimorgan gives the average probability of a crossover as 1 % over every million base pairs.
• The centimorgan is also often used to imply distance along a chromosome, but the number of base pairs it corresponds to varies widely.
• :The argument in the rest of your quote is as follows : One centiMorgan ( cM ) is defined as the genetic distance between two loci that causes there to be a 1 % chance of a recombination event between these loci.
• The relationship is only rough as the physical chromosomal distance corresponding to one centimorgan varies from place to place in the genome, and also varies between men and women since recombination during gamete formation in females is significantly more frequent than in males.
• Morton et al . calculated that the female genome is 4782 centimorgans long, while the male genome is only 2809 centimorgans long . " Plasmodium falciparum " has an average recombination distance of ~ 15 kb per centimorgan : markers separated by 15 kb of DNA ( 15, 000 nucleotides ) have an expected rate of chromosomal crossovers of 0.01 per generation.