colicins การใช้

• Colicins are released into the environment to reduce competition from other bacterial strains.
• ApoL1 has a membrane pore forming domain functionally similar to that of bacterial colicins.
• The TonB protein also interacts with some colicins.
• The colicins similarly form pores in lipid bilayers.
• This protein may form the receptor for S4 colicins in " Escherichia coli ".
• BACTIBASE database is an open-access database for bacteriocins including colicins ( view complete list ).
• In the 1970s, they were investigated, along with some colicins, as potential chemotherapeutic agents.
• The arrangement of the ?-helices in Bcl-X ( L ) resembles that for diphtheria toxin and the colicins.
• The Professor Kleanthous Research Group at the University of York study colicins extensively as a model system for characterising and investigating protein-protein interactions and recognition.
• Colicins bind to translocate to the cytoplasm or cytoplasmic membrane, where they exert their cytotoxic effect, including depolarisation of the cytoplasmic membrane, DNase activity, RNase activity, or inhibition of murein synthesis.
• Lederberg also founded and directed the now defunct Plasmid Reference Center at Stanford University, where she maintained, named, and distributed plasmids of many types, including those coding for antibiotic resistance, heavy metal resistance, virulence, conjugation, colicins, transposons, and other unknown factors.