cytostatic การใช้

• Mercaptopurine is a cytostatic drug that is an antimetabolite.
• Active hygienic products generally contain cytostatic substances.
• Zero-order release kinetics were achieved when embedding the cytostatic agent 5-fluorouracil.
• It does not affect cytostatic activity.
• Use as a cytostatic in the treatment of refractory promyelocytic ( M3 ) subtype of acute myeloid leukemia.
• The substance they contain ( podophyllotoxin or podophyllin ) is used as a purgative and as a cytostatic.
• Chemotherapy of cancer, treatment of skin diseases and treatment of infections are common use cases of cytostatic drugs.
• Animal and clinical studies show that rapalogs are primarily cytostatic, and therefore effective as disease stabilizers rather than for regression.
• The first compound to be tested in this first antimetastatic drug screen was the cytostatic agent razoxane [ ICRF 159 ].
• Aminopterin, a cytostatic drug with anti-folate effect, was used during the 1950s and 1960s to induce therapeutic abortions.
• "' Doxifluridine "'is a cytostatic agent used in chemotherapy in several Asian countries including China and South Korea.
• It was discovered that rapamycin had an anticancer activity and was a non-cytotoxic agent with cytostatic activity against several human cancer types.
• Study shows that metabolites of the lipoxygenase pathway are involved with the antiproliferation induce by PUFA . However, PUFA cytostatic activity is not tumor-specific.
• The principal physiological function of glyoxalase I is the detoxification of methylglyoxal, a reactive 2-oxoaldehyde that is cytostatic at low concentrations and cytotoxic at millimolar concentrations.
• While cytostatic agents such as zinc pyrithione are first line, keratolytics ( salicylic acid and sulfur ) can also be used in the treatment of dandruff and seborrheic dermatitis.
• Breast cancer  One study indicates nitric oxide ( NO ) is able to have a cytostatic effect on the human breast cancer cell line MDA-MB-231.
• Introduction of miR-1 and miR-133a into an embryonal rhabdomyosarcoma-derived cell line is cytostatic, which suggested a strong tumour-suppressive role for these microRNAs.
• Tetrazolium dye assays can also be used to measure cytotoxicity ( loss of viable cells ) or cytostatic activity ( shift from proliferation to quiescence ) of potential medicinal agents and toxic materials.
• Immunogenic cell death or immunogenic apoptosis is a form of cell death caused by some cytostatic agents such as anthracyclines, oxaliplatin and bortezomib, or radiotherapy and photodynamic therapy ( PDT ).
• The histone deacetylase inhibitors are a new class of cytostatic agents that inhibit the proliferation of tumor cells in culture and in vivo by inducing cell cycle arrest, differentiation and / or apoptosis.