danazol การใช้

• Danazol is an effective treatment to shrink fibroids and control symptoms.
• The use of danazol for endometriosis has been linked to an increased risk of ovarian cancer.
• People with frequent attacks of angioedema are often treated using attenuated androgens, such as danazol and oxandrolone.
• Danazol, like most other androgenic drugs, has been linked with an increased risk of liver tumors.
• As can be seen, the percentage of free testosterone is tripled in women being treated with danazol.
• He also showed that the drug Danazol was useful in the management of endometriosis and fibrocystic breast disease.
• Danazol shrinks fibroids by blocking estrogen, but it shrinks breasts and causes growth of facial hair and acne.
• Danazol is considered to act significantly as an agonist of the GR, and thus, as a glucocorticoid.
• Juvisync should not be used with : strong CYP3A4 inhibitors, cyclosporine, danazol, gemfibrozil and other fibrates.
• Future attacks of hereditary angioedema can be prevented by the use of androgens such as danazol, oxandrolone or methyltestosterone.
• If refractory to both these therapies, other options include rituximab, danazol, cyclosphosphamide, azathioprine, or ciclosporin.
• Following this, other immunosuppressants are considered, such as rituximab, danazol, cyclophosphamide, azathioprine, or cyclosporine.
• Danazol, an antiestrogen and weak androgen, has also been found to be effective in the treatment of macromastia.
• In accordance with the above, clinical studies have demonstrated that danazol directly and markedly inhibits testicular steroidogenesis " in vivo ".
• Menstruation and accompanying lung collapse can be suppressed with hormone therapy, like with Lupron Depot, danazol or extended cycle combined oral contraceptive pills.
• Although in contradiction with the above data, another study found that danazol weakly inhibited aromatase as well, with 44 % inhibition at a concentration of 10 ?M.
• Danazol may also be prescribed to treat this condition and it is usually considered in patients on whom the non-medical treatment fails and the symptoms are intense.
• The possibilities include oral contraceptives, progestins only, danazol ( a derivative of testosterone ), and gonadotropin-releasing hormone ( GnRH ) agonists, which induce a pseudomenopause.
• Gestrinone is described as similar in action and effect to danazol, which is also used in the treatment of endometriosis, but is reported to have fewer androgenic side effects in comparison.
• Since danazol is metabolized by the liver, it cannot be used by patients with liver disease, and in patients receiving long-term therapy, liver function must be monitored on a periodic basis.