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dedifferentiate การใช้

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  • These alterations indicate intense metabolic activity, appearing to dedifferentiate and resemble meristematic cells.
  • The dedifferentiated cells still retain their original specification.
  • Myoblasts in skeletal muscle that do not form muscle fibers dedifferentiate back into myosatellite cells.
  • GCCL was first confirmed as an epithelial tumor ( and not a dedifferentiated pleomorphic sarcoma ) in 1961.
  • The tumor-induced stromal change hypothesis claims that tumor cells can dedifferentiate into fibroblasts and, themselves, secrete more collagen.
  • In newts, muscle tissue is regenerated from specialized muscle cells that dedifferentiate and forget the type of cell they had been.
  • Beneath that layer are adult cells that " dedifferentiate " to form stem cells, which then can regenerate specialized tissues of many types.
  • But even though some of the limb cells are able to dedifferentiate, they are not able to fully dedifferentiate to the level of multipotent progenitor cells.
  • But even though some of the limb cells are able to dedifferentiate, they are not able to fully dedifferentiate to the level of multipotent progenitor cells.
  • The major strategies of regenerative medicine include dedifferentiating injury site cells, transplanting stem cells, implanting lab-grown tissues and organs, and implanting bioartificial tissues.
  • Thus failure to isolate plant stem cells from meristematic tissues prompted scientists to administer plant cell culture by using callus ( dedifferentiated cells ) as an alternative to plant stem cells.
  • In response to a hormogonium-inducing factor ( HIF ) secreted by plant hosts, cyanobacterial symbionts differentiate into hormogonia and then dedifferentiate back into vegetative cells after about 96 hours.
  • "' Callus "', or dedifferentiated cells, are somatic cells that undergo dedifferentiation to give rise to totipotent embryogenic cells, which temporarily gains the ability to proliferate and / or regenerate an embryo.
  • After injury, mature terminally differentiated kidney cells dedifferentiate into more primordial versions of themselves and then differentiate into the cell types needing replacement in the damaged tissue Macrophages can self-renew by local proliferation of mature differentiated cells.
  • Finally, currently most cloning techniques poorly preserve epigenetic modifications ( though there are some that are better for example altering epigenetics is a primary mode by which dedifferentiation techniques dedifferentiate cells, so expect a somewhat different phenotype with these ).
  • Rhabdoid cells often express protein products suggestive of aggressive, dedifferentiated cells, including neuroendocrine tumor-related products Vimentin, an intermediate filament protein usually associated with non-carcinomatous tumors ( i . e . sarcoma ), is ubiquitous in rhabdoid cells.
  • "" Counterinstitutions are intended to dedifferentiate some parts of the formally organised domains of action, remove them from the clutches of the steering media, and return these'liberated areas'to the action co-ordinating medium of reaching understanding " ".
  • Since embryogenic cells were considered totipotent cells based on their ability to regenerate or develop into an embryo under given conditions, dedifferentiated cells were generally regarded as stem cells of plant : " & we propose to extend the concept of stem cells to include embryogenic stem cells that arise from plant somatic cells.
  • However, brief expression of a single transcription factor, the ELT-7 GATA factor, can convert the identity of fully differentiated, specialized non-endodermal cells of the pharynx into fully differentiated intestinal cells in intact larvae and adult roundworm " Caenorhabditis elegans " with no requirement for a dedifferentiated intermediate.
  • Cells can become anaplastic in two ways : neoplastic tumor cells can dedifferentiate to become anaplasias ( the dedifferentiation causes the cells to lose all of their normal structure / function ), or cancer stem cells can increase in their capacity to multiply ( i . e ., uncontrollable growth due to failure of differentiation ).
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