degranulation การใช้

• At low concentrations, MCD peptide can stimulate mast cell degranulation.
• Interaction with SP receptors induces vasodilation and allows for plasma extravasation and mastocyte degranulation.
• After degranulation a CD63 marker ( labeld antibodies ) is added to the test tube.
• Dysfunction in the neutrophil biochemical pathway myeloperoxidase as well as reduced degranulation are associated with hyperglycemia.
• In addition, migration and degranulation of neutrophils can be suppressed in the presence of C3a.
• The variability in platelet concentrating techniques may alter platelet degranulation characteristics that could affect clinical outcomes.
• In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils.
• Absorption of this substance would exert an effect of perifollicular mast cell degranulation with releas of histamine.
• For example, IgE is responsible for an allergic response consisting of mast cell degranulation and histamine release.
• CGRP binding to its receptor will also promote mast cell degranulation and infiltration by neutrophils and other immune cells.
• Other membrane activation events can either prime mast cells for subsequent degranulation or act in synergy with Fc?RI signal transduction.
• It is a lysosomal protein stored in azurophilic granules of the neutrophil and released into the extracellular space during degranulation.
• Neurotensin is involved in many processes including mast cell degranulation and regulation of central nervous system dopaminergic and cholinergic circuits.
• Antibodies will also trigger vasoactive amine degranulation to contribute to immunity against certain types of antigens ( helminths, allergens ).
• They block a calcium channel essential for mast cell degranulation, stabilizing the cell, thus preventing the release of histamine.
• If the degranulation is widespread, it can cause a shock-like syndrome similar to that of an allergic reaction.
• The degranulation of mast cells is very easily triggered, as was evidenced by the controversial Nature paper by Jacques Benveniste.
• Interleukin-8 is a key mediator associated with inflammation where it plays a key role in neutrophil recruitment and neutrophil degranulation.
• Crosslinking of the Fc?RI via IgE-antigen complexes leads to degranulation of mast cells or basophils and release of inflammatory mediators.
• Under laboratory conditions, degranulation of isolated basophils can also be induced with antibodies to the Fc?RI?, which crosslink the receptor.