desmopressin การใช้

• Desmopressin is a synthetic analog of the natural antidiuretic hormone vasopressin.
• DI may be treated with a medication called desmopressin acetate ( DDAVP ).
• If these parameters are unchanged, desmopressin ( an ADH analogue ) is administered.
• Desmopressin is degraded more slowly than recombinant vasopressin, and requires less frequent administration.
• This may be treated with the drug desmopressin,
• In some cases of adipsic DI, the patient may also fail to respond to desmopressin.
• Most cases of gestational DI can be treated with desmopressin ( ddAVP ), but not vasopressin.
• Desmopressin is contraindicated in vWD type 2b because of the risk of aggravated thrombocytopenia and thrombotic complications.
• CDI is often treated with desmopressin acetate a synthetic vasopressin known as DDAVP administered via nasal spray.
• Desmopressin is also available as a preparation for intranasal administration ( Stimate ) and as a preparation for intravenous administration.
• Patients must stop taking desmopressin if they develop severe vomiting and diarrhea, fever, the flu, or severe cold.
• Desmopressin may be administered intravenously in the hope of reversing the clotting disturbance that accompanies kidney failure ( uraemic coagulopathy ).
• In rare cases, however, an abnormality in the thirst mechanism causes gestational DI, and desmopressin should not be used.
• The hemostatic efficacy of desmopressin, an analog of vasopressin, was first discovered in Italy in 1977 by Mannucci and colleagues.
• Additionally, desmopressin is able to enhance ACTH and cortisol release in normal subjects following oCRH administration, but not in patients with anorexia nervosa.
• Desmopressin is probably not effective in vWD type 2M and is rarely effective in vWD type 2N . It is totally ineffective in vWD type 3.
• There are complex treatments that can be done including a combination of therapies, estrogen-progesterone preparations, desmopressin, and Von Willebrand factor concentrates.
• In patients who can produce von Willebrand factor that is structurally and functionally normal, desmopressin acetate sets off its release from storage sites in blood vessels.
• To distinguish between the main forms, desmopressin stimulation is also used; desmopressin can be taken by injection, a nasal spray, or a tablet.
• To distinguish between the main forms, desmopressin stimulation is also used; desmopressin can be taken by injection, a nasal spray, or a tablet.