downregulation การใช้

• This phenomenon is known as ligand-induced desensitization or downregulation.
• Downregulation refers to the decrease in the number of receptor sites.
• It also may participate in the process of GAD67 downregulation in schizophrenia.
• Upregulation and downregulation can also happen as a response to toxins or hormones.
• Downregulation of BDNF, therefore, may cause decreased connectivity in the brain.
• Specifically, downregulation of hedgehog results in reduced eyes.
• Downregulation of miR-10a has been found in nucleus to the cytoplasm.
• This indicates that downregulation of Sulf1 is not a ubiquitous process in carcinogenesis.
• Indeed, downregulation of caveolin-1 leads to less efficient migration in vitro.
• Downregulation of polymorphisms, cytokines, or both.
• SREBP-1c mediates MEF2C downregulation through a mechanism that remains to be determined.
• The truncation of the receptor protein results in the inability of downregulation after stimulation.
• Upregulation in the aberrant microRNAs was more common than downregulation in the cancer patients.
• This downregulation has not been fully explained.
• By contrast, JDP2-knockout mice exhibit in downregulation of p53 and p21 proteins.
• There was also a GPR84 downregulation in dentritic cell derived from FcRgamma chain KO mice.
• By extension, downregulation of TXN2 can lead to increased ROS generation and cell death.
• In particular, upregulation of hypoxia upregulates DDIT4, and subsequent downregulation of mTOR via Rheb.
• Cancer cell lines with downregulation of Sulf1 were investigated in the same fashion as ovarian cancer.
• Downregulation of mesolimbic dopamine receptors can result in a decrease in the sensitivity to natural reinforcers.