dromotropic การใช้

• Diltiazem has negative inotropic, chronotropic, and dromotropic effects.
• Agents that are dromotropic are often ( but not always ) inotropic and chronotropic.
• It also causes a negative dromotropic effect through the inhibition of AV-nodal conduction.
• For instance, parasympathetic stimulation is usually negatively chronotropic and dromotropic, but because the vagus nerve does not innervate ventricular myocardium has no effect on inotropy.
• Non-dihydropyridine calcium channel blockers such as verapamil block the slow inward calcium current in cardiac tissues, thereby having a negatively dromotropic, chronotropic and inotropic effect.