dysgenesis การใช้

• In contrast XX gonadal dysgenesis has a normal female chromosome situation.
• Congenital hypothyroidism caused by thyroid dysgenesis can be associated with PAX8.
• The P element gives rise to a phenotype known as hybrid dysgenesis.
• Women with 46 XX gonadal dysgenesis experience primary amenorrhea with hypergonadotropic hypogonadism.
• Mutations in the FOXE3 gene are associated with anterior segment mesenchymal dysgenesis.
• The term dysgenesis is used to describe abnormal organ development during embryonic growth and development.
• Although similar in some ways to mixed gonadal dysgenesis, the conditions can be distinguished histologically.
• Microcornea and iridocorneal dysgenesis also occur.
• In the rabbit model, disorders observed involving NR4A1 expression include testicular dysgenesis, and cryptorchidism.
• Other disorders that result from STRA6 mutations include pulmonary dysgenesis, cardiac malformations, and mental retardation.
• At this point it is usually possible for a physician to make a diagnosis of XX gonadal dysgenesis.
• Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
• Two ocular syndrome multiple congenital ocular anomalies ( MCOA ), originally called equine anterior segment dysgenesis ( ASD ).
• Abnormal gonads ( due to gonadal dysgenesis and androgen insensitivity syndrome ) have a high risk of developing a dysgerminoma.
• Another disorder is that of thyroid dysgenesis which can result in various presentations of one or more misplaced accessory thyroid glands.
• Dysgenesis of the vesicle later in development may result in coloboma, a separate and less severe malformation of the ocular structures.
• Nonstop mutations have been linked with several congenital diseases including congenital adrenal hyperplasia, variable anterior segment dysgenesis, and mitochondrial neurogastrointestinal encephalomyopathy.
• From the 1940s until the late 1980s, DES was FDA-approved as ovarian dysgenesis, premature ovarian failure, and after oophorectomy.
• The PAX8 gene is also associated congenital hypothyroidism due to thyroid dysgenesis because of its role in growth and development of the thyroid gland.
• When the Y fragment is minimal and nonfunctional, the child is usually a girl with the features of Turner syndrome or mixed gonadal dysgenesis.