eflornithine การใช้

• Eflornithine represents a case where it may be possible to serve both interests at once.
• Eflornithine is also effective in combination with other drugs, such as melarsoprol and nifurtimox.
• The loss of this gene due to specific mutations causes resistance to eflornithine in several trypanosomes.
• This has made eflornithine a supported chemopreventive therapy specifically for colon cancer in combination with other medications.
• Ornidyl, intended for injection, was supplied in the strength of 200 mg eflornithine hydrochloride per ml.
• A seven-day treatment of eflornithine can cure a patient even in the late stages of the disease.
• Inactivation of ODC by difluoromethylornithine ( eflornithine ) is used to treat cancer and facial hair growth in postmenopausal females.
• The drug, eflornithine, is so effective at reviving even comatose patients that it is known as the resurrection drug.
• It is treated with the drug melarsoprol or the newer, more effective eflornithine, which can be hard to obtain.
• Bristol-Myers Squibb will supply eflornithine free in Africa for the next three years, said company spokesman Robert Laverty.
• It was found that inhibition of ODC by eflornithine does not kill proliferating cells, making eflornithine ineffective as a chemotherapeutic agent.
• It was found that inhibition of ODC by eflornithine does not kill proliferating cells, making eflornithine ineffective as a chemotherapeutic agent.
• A typical course of eflornithine treatment is an injection a day for seven days, for a total cost of about $ 70.
• Markham said Aventis would arrange for the production of three drugs _ pentamidine, melarsoprol and eflornithine _ essential to treating sleeping sickness.
• ODC is also an enzyme indispensable to parasites like trypanosoma, giardia, and plasmodium, a fact exploited by the drug eflornithine.
• Ornidyl, the injectable form of eflornithine hydrochloride, is licensed by Sanofi-Aventis, but is currently discontinued in the US.
• Eflornithine has been dubbed " the resurrection drug " because of its remarkable success at bringing sleeping sickness victims out of comas.
• Combination therapy with eflornithine and nifurtimox is safer and easier than treatment with eflornithine alone, and appears to be equally or more effective.
• Combination therapy with eflornithine and nifurtimox is safer and easier than treatment with eflornithine alone, and appears to be equally or more effective.
• For sleeping sickness, eflornithine is the only drug besides melarsoprol that is able to kill the parasite trypanosome after it has invaded the brain.