endothelin การใช้

• Such regulatory genes include endothelin receptor type B ( EDNRB ).
• BQ-123 is a selective ET A endothelin receptor antagonist.
• Endothelin 2 has functions within the ovarian follicle related to ovulation.
• She primarily tests rats and uses the Endothelin-1 stroke model.
• The peptide endothelin constricts muscles in blood vessels, increasing blood pressure.
• NEP-like enzymes include the endothelin-converting enzymes.
• Increased endothelin and decreased vasodilation has been documented.
• Endothelin and prostanoids cause vasoconstriction in placental arteries, while nitric oxide causes vasodilation.
• Among numerous diseases potentially occurring from endothelin dysregulation are
• Endothelin receptor activation mediates strong pulmonary vasoconstriction and positive inotropic effect on the heart.
• As such, endothelin receptor antagonists such as Ambrisentan are known to be teratogenic.
• It is an endothelin receptor antagonist selective for subtype A ( ET A ).
• Endothelin 2 is a member of the endothelin protein family of secretory vasoconstrictive peptides.
• Endothelin 2 is a member of the endothelin protein family of secretory vasoconstrictive peptides.
• It has potent activity as an endothelin receptor antagonist and anti-osteoporosis agent.
• The precise effects of endothelin B receptor activation depends on the type of cells involved.
• Endothelial cells induce expression of endothelin-1, which leads to NO production and vasodilation.
• Endothelial cells convert preproendothelin to proendothelin and subsequently to mature endothelin, which the cells release.
• Endothelin-1 receptor antagonists ( Bosentan ) are used in the treatment of pulmonary hypertension.
• It is an endothelin receptor antagonist.