engraftment การใช้

• Such reactions may protect against tumor cell engraftment by eliminating implanted cells.
• Test offerings include Tuberculosis testing and Bone Marrow Engraftment ( chimerism ) monitoring.
• The first is, can achieve engraftment of the baboon bone marrow in humans?
• She had a higher chance of engraftment and a far lower chance of rejection.
• Finally, osteoclast inhibition by the bisphosphonate alendronate has correlated with decreased HSCs and bone marrow engraftment.
• Conversely, stimulation of HSC CaSR via its agonist cinacalcet increases migration and engraftment of these cells in the bone marrow.
• In comparison with BM derived HSCs recipients, PBSCs recipients afflicted with myeloid malignancies reported a faster engraftment and better overall survival.
• While the engraftment of HSCs at these sites are still being elucidated, the interaction between the chemokine chemotactic induction of CXCL12.
• Subcutaneous PDTX rarely produce metastasis in mice, does not simulate the initial tumor microenvironment, and has engraftment rates 40-60 %.
• However, transplant with cord blood sometimes requires longer periods of time for engraftment, which may increase the potential for complications due to infection.
• "We were able to get engraftment in those mice as good as we get from fresh cord blood samples, " he said.
• This property, known as engraftment, holds out the possibility that stem cells can be put to therapeutic use long before their behavior is fully understood.
• Bone Marrow Engraftment monitoring assesses the relative ratio of donor and recipient cell populations in the post-transplant peripheral blood or bone marrow of the patient.
• 24.2009 " A modified haploidentical nonmyeloablative transplantation without T cell depletion for high-risk acute leukemia : successful engraftment and mild GVHD"
• There is a patent that identified genes associated with midbrain dopamine neurons for engraftment by looking at the differentiation of hiPSC in floor plate midbrain progenitor cells.
• In terms of clinical use, because of its characterization as a hematopoetic factor, IL-1 was given to patients after bone marrow transplantation to improve the engraftment.
• After this breakthrough the engraftment rate was improved even further thanks to the development of a nanoscale shielding using biomaterials approved by the U . S . Food and Drug Administration ( FDA ).
• Taken together, these results suggest that the high calcium ion concentration found in the endosteal niche due to osteoclast activity acts as a homing signal to HSCs for engraftment into the bone marrow via the CaSR.
• However, this was at the expense of increased rate of GVHD . Also, the use of UCB requires less stringent HLA loci matching, although the time of engraftment is longer and graft failure rate is higher.
• Non-myeloablative bone marrow transplantation uses lower doses of total body irradiation, typically about 2 Gy, which do not destroy the host bone marrow but do suppress the host immune system sufficiently to promote donor engraftment.