epha การใช้

• Epha divination, similar to the evangelical denominations.
• Ephs can be divided into two subclasses, EphAs and EphBs ( encoded by the EphB2.
• ODIN is known to regulate the epidermal growth factor receptor ( EGFR ) and EphA receptor signaling pathways.
• Additionally, EphA receptors were shown to exert opposite effects on motor neuron growth cones by reducing growth cone size.
• FEANTSA is a member of the Platform of European Social NGOs, EAPN ( European Anti Poverty Network ) and EPHA ( European Public Health Alliance ).
• Typically, forward signaling by both EphA and EphB receptors mediates growth cone collapse while reverse signaling via ephrin-A and ephrin-B induces growth cone survival.
• Forward signaling between Ephrin-A and EphA, along the anterior-posterior axis, has been found to inhibit retinal axon branch formation posterior to a terminal zone.
• In contrast EphBs typically bind with lower affinity than EphAs / ephring-As since they utilize an " induced fit " mechanism that requires a greater conformational change of EphBs to bind ephrin-Bs.
• While the project started under the eyes of NYSDOT and EPHA, when the new parkway was complete, the East Hudson Parkway Authority had been disestablished in 1979 and control of the Sprain Brook had been turned back to NYSDOT.
• EphAs / ephrin-As typically bind with high affinity, which can partially be attributed to the fact that ephrinAs interact with EphAs by a " lock-and-key " mechanism that requires little conformational change of the EphAs upon ligand binding.
• EphAs / ephrin-As typically bind with high affinity, which can partially be attributed to the fact that ephrinAs interact with EphAs by a " lock-and-key " mechanism that requires little conformational change of the EphAs upon ligand binding.
• EphAs / ephrin-As typically bind with high affinity, which can partially be attributed to the fact that ephrinAs interact with EphAs by a " lock-and-key " mechanism that requires little conformational change of the EphAs upon ligand binding.
• Although several members of Ephs and ephrins contribute to motor neuron guidance, ephrin-A5 reverse signaling has been shown to play a critical role in the survival of motor neuron growth cones and to mediate growth cone migration by initiating repellence in EphA-expressing migrating axons.
• This finding that ephrin A5 promotes growth cone survival that is opposite of EphA signaling and mediated directly by ephrin A5 reverse signaling has important implications for axon guidance as it provides a mechanism by which migrating axons expressing EphAs would preferentially avoid ephrin A5 expressing cells and possibly migrate towards cells with lower expression of ephrin A5.
• This finding that ephrin A5 promotes growth cone survival that is opposite of EphA signaling and mediated directly by ephrin A5 reverse signaling has important implications for axon guidance as it provides a mechanism by which migrating axons expressing EphAs would preferentially avoid ephrin A5 expressing cells and possibly migrate towards cells with lower expression of ephrin A5.
• Of the eight ephrins that have been identified in humans there are five known ephrin-A ligands ( ephrin-A1-5 ) that interact with nine EphAs ( EphA1-8 and EphA10 ) and three ephrin-B ligands ( ephrin-B1-3 ) that interact with five EphBs ( EphB1-4 and EphB6 ).
• Some restoration work has been carried and it is possible to visit the newly restored gravestones of two famous locals : Johannes Thienemann ( 1863-1938 ), the German ornithologist who founded the Rossitten Bird Observatory; and Franz Epha, the legendary dune inspector who was able to stop the huge sand dunes from moving by stabilising them with plants.
• EphA / ephrinA interaction typically occur with higher affinity than EphB / ephrin-B interactions which can partially be attributed to the fact that ephrin-As bind via a " lock-and-key " mechanism that requires little conformational change of the EphAs in contrast to EphBs which utilize an " induced fit " mechanism that requires a greater amount of energy to alter the conformation of EphBs to bind to ephrin-Bs.
• EphA / ephrinA interaction typically occur with higher affinity than EphB / ephrin-B interactions which can partially be attributed to the fact that ephrin-As bind via a " lock-and-key " mechanism that requires little conformational change of the EphAs in contrast to EphBs which utilize an " induced fit " mechanism that requires a greater amount of energy to alter the conformation of EphBs to bind to ephrin-Bs.