fibrinoid การใช้

• The mucosa of the microvasculitis with fibrinoid necrosis.
• Interlobular and afferent arterioles show fibrinoid necrosis and intimal hyperplasia and are often occluded by thrombi.
• They are pathognomic foci of fibrinoid necrosis found in many sites, most often the myocardium.
• In malignant hypertension these hyperplastic changes are often accompanied by fibrinoid necrosis of the arterial intima and media.
• The region of fibrinoid degeneration where trophoblasts meet decidua is called " Nitabuch's layer ".
• Endothelial injury can occur as a consequence of severe elevations in blood pressure, with fibrinoid necrosis of the arterioles following.
• Fibrinoid necrosis also occurs in the walls of arterioles in malignant hypertension ( blood pressure greater than 200 / 130 mmHg ).
• Although they are usually indicative of fibrinoid necrosis associated with malignant hypertension, Siegrist streaks also occur in patients with temporal arteritis.
• Fibrinoid necrosis is a special form of necrosis usually seen in immune reactions involving blood vessels, known as Type III hypersensitivity reactions.
• Involvement of the endocardium typically results in fibrinoid necrosis and verrucae formation along the lines of closure of the left-sided heart valves.
• As observed under methods of histopathology, acute necrotizing vasculitis within the affected tissues is observed concomitant to neutrophilic infiltration, along with notable eosinophilic deposition ( fibrinoid necrosis ).
• In small vessel vasculitis, fibrin plugs frequently occur in the vessel lumen, but the term fibrinoid is usually used to refer to material outside the lumen of a vessel.
• The renal lesion associated with malignant hypertension consists of fibrinoid necrosis of the afferent arterioles, sometimes extending into the glomerulus, and may result in focal necrosis of the glomerular tuft.
• The response is characterized by an inflammatory infiltrate of mostly macrophages and natural killer cells ( with small numbers of T cells ), intravascular thrombosis, and fibrinoid necrosis of vessel walls.
• Common sites undergoing fibrinoid necrosis are, SLE, Aschoff bodies seen in rheumatic heart disease, Arthus reaction, serum sickness, polyarteritis nodosa, poststreptococcal glomerulonephritis, hyperacutely rejected grafts, malignant hypertension ( > 200 / 130 mm Hg ).
• However, the term " histiocyte " has been used for multiple purposes in the past, and some cells called " histocytes " do not appear to derive from monocytic-macrophage lines . ( The term Histiocyte can also simply refer to a cell from monocyte origin outside the blood system, such as in a tissue ( as in rheumatoid arthritis as palisading histiocytes surrounding fibrinoid necrosis of rheumatoid nodules ).