flunitrazepam การใช้

• Previously only brotizolam, flunitrazepam and triazolam were classed as dangerous drugs.
• Extreme caution should be exercised by drivers after taking flunitrazepam.
• Flunitrazepam is lipophilic and is metabolised hepatically via oxidative pathways.
• Benzodiazepines more likely to cause euphoria are flunitrazepam, alprazolam and clonazepam.
• Flunitrazepam is also known to induce anterograde amnesia making police interrogations more difficult.
• In addition to alcohol the characters were also under the influence of flunitrazepam.
• Nitrazepam and flunitrazepam were significantly more commonly implicated in suicide related deaths than natural deaths.
• Nitrazepam and temazepam were the most prevalent drugs detected, followed by oxazepam and flunitrazepam.
• This side-effect is not unique to flunitrazepam but also occurs with other hypnotic drugs.
• Benzodiazepines and in particular nitrazepam and flunitrazepam should therefore be prescribed with caution in the elderly.
• Flunitrazepam seems to have a particularly high risk of road traffic accidents compared to other hypnotic drugs.
• Rohypnol, also known as flunitrazepam, is not manufactured in the United States, nor available by prescription.
• In certain countries, triazolam, flunitrazepam, flutoprazepam and midazolam are also restricted or controlled to certain degrees.
• In 1991, the sales of flunitrazepam and triazolam fell, but the sales of five unrestricted benzodiazepines increased.
• These regulations were applied initially only to brotizolam, triazolam and flunitrazepam as they were the major benzodiazepines of abuse.
• While 80 % of flunitrazepam that is taken orally is absorbed, bioavailability in suppository form is closer to 50 %.
• Flunitrazepam and other sedative hypnotic drugs are detected frequently in cases of people suspected of driving under the influence of drugs.
• Nifoxipam produces strong tranquillising and sleep-prolonging effects and has much lower toxicity compared to lormetazepam and flunitrazepam in mice.
• In addition to recreational use, flunitrazepam, another member of the benzodiazepine family, may be taken to facilitate criminal activity.
• Rebound insomnia, worse than baseline insomnia, typically occur after discontinuation of flunitrazepam even after short-term single nightly dose therapy.