glycyl การใช้

• Active site TMSs are rich in glycyl residues in variable but conserved arrangements.
• For example, the acyl group of glycine is glycyl, and of lysine is lysyl.
• Glycyl-tRNA synthetase has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
• This would yield a coordination number of six for the zinc in the carboxypeptidase A-dipeptide glycyl-L-tyrosine complex.
• EEF1D has been shown to interact with Glycyl-tRNA synthetase, EEF1G and KTN1, and is predicted to interact with TMEM63A.
• This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids.
• When bound to dipeptide glycyl-L-tyrosine, the amino nitrogen of the dipeptide and the carbonyl oxygen replaced the water ligand.
• "' Copper peptide GHK-Cu "'is a naturally occurring copper complex of a glycyl-L-histidyl-L-lysine plasma.
• Glycyl-tRNA synthetase has been shown to interact with EEF1D . Mutant forms of the protein associated with peripheral nerve disease have been shown to aberrantly bind to the transmembrane receptor protein neuropilin 1.
• Another synthesis, due to Nordlander and co-workers, began with the Friedel-Crafts acylation of benzene by " N "-( trifluoroacetyl ) glycyl chloride in the presence of aluminum chloride.
• This enzyme catalyses the successive transfer of two glycine moieties from charged tRNAs to N-acetylmuramoyl-L-alanyl-D-isoglutaminyl-L-lysyl-( N 6-glycyl )-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine.
• The Anaerobic Enzymology bridging project will explore radical-dependent enzymology, which allows the execution of unusual chemical transformations via an iron-sulfur cluster cleaving S-Adenosyl methionine ( SAM ) and producing a radical intermediate, or alternatively, abstraction of a hydrogen from glycine producing a glycyl radical.
• The subunits all share a common topology, possessing two transmembrane domains ( one about 30-50 residues from their N-termini, the other near residues 320-340 ), a large extracellular loop and intracellular amino termini ( Figure 1 ) The extracellular receptor domains between these two segments ( of about 270 residues ) are well conserved with several conserved glycyl residues and 10 conserved cysteyl residues.
• The experiment showed that C-1 of glycine was found almost exclusively in the glycyl portion of hadacidin while formate, the 3-carbon of serine, and the 2-carbon of glycine were incorporated into both the glycyl and formyl portions of the hydroxamate . " N "-Hydroxyglycine was incorporated into hadacidin at a rate equal to that for glycine in 3-hr periods and to a much greater extent in longer time periods.
• The experiment showed that C-1 of glycine was found almost exclusively in the glycyl portion of hadacidin while formate, the 3-carbon of serine, and the 2-carbon of glycine were incorporated into both the glycyl and formyl portions of the hydroxamate . " N "-Hydroxyglycine was incorporated into hadacidin at a rate equal to that for glycine in 3-hr periods and to a much greater extent in longer time periods.
• After binding to Glycyl-Prolyl-Prolyl-Prolyl-Prolyl-Prolyl-registers on tracker proteins, Profilin-ATP-actin is delivered ( " loaded " ) to the unclamped end of the other sub-filament, whereupon ATP within the already clamped terminal subunit of the other subfragment is hydrolyzed ( " fired " ), providing the energy needed to release that arm of the end-tracker, which then can bind another Profilin-ATP-actin to begin a new monomer-addition round.
• Strains which have been studied failed to utilize dextrin, D-aspertic acid, glycyl-L-proline, L-alanine, L-arginine, L-glutamic acid, L-histidine, L-serine, mucic acid, p-hydroxy-phenylacetic acid, methyl pyruvate, citric acid, D-malic acid, L-malic acid, propionic acid or formic acid . " R . bangladeshense " can grow in the presence of lincomycin and potassium tellurite, but not with 1 % sodium lactate, troleandomycin, tetrazolium violet, tetrazolium blue, Nalidixic acid, lithium chloride and sodium butyrate.
• They are unable to utilize D-maltose, D-trehalose, D-cellobiose, gentiobiose, sucrose, D-raffinose, ?-D-glucose, D-turanose, D-melibose, mannose, galactose, 3-methyle glucose, inosine, D-aspartic acid, glycyl-L-proline, L-alanine, L-arginine, L-serine, pectine, D-saccharic acid, p-hydroxy-phenylacetic acid, methyl pyruvate, citric acid, bromo-succinic acid, acetoacetic acid or propionic acid . " R . lentis " can grow in the presence of the antibiotic compounds lincomycin, tetrazolium violet and tetrazolium blue but not with 1 % sodium lactate, troleandomycin, lithium chloride, potassium tellurite or sodium butyrate.