haematopoiesis การใช้

• Thus indicating the potency of definitive haematopoiesis from this region.
• The most significant function of the aorta gonad mesonephros region is its role in definitive haematopoiesis.
• This isolates NO signalling as the key factor controlling haematopoiesis, and not just the presence of circulation.
• Definitive haematopoiesis produces hematopoietic stem cells that have the capacity to differentiate any blood cell lineage in the adult circulation.
• MDSCs strongly expand in pathological situations such as chronic infections and cancer, as a result of an altered haematopoiesis.
• The AGM region plays an important role in embryonic development, being the first autonomous intra-embryonic site for definitive haematopoiesis.
• Definitive haematopoiesis is the second wave of embryonic haematopoiesis and give rise to all hematopoietic stem cells in the adult hematopoietic system.
• Definitive haematopoiesis is the second wave of embryonic haematopoiesis and give rise to all hematopoietic stem cells in the adult hematopoietic system.
• M-CSF, LIF ), bone marrow stromal cells have been described to be involved in human haematopoiesis and inflammatory processes.
• This + 23 RUNX1 enhancer contains conserved motifs that encourage binding of various haematopoiesis related regulators such as Smad6 to target itself for proteolysis.
• The circulating cells in the blood all come from the stem cells in the bone marrow; see haematopoiesis for details of this process.
• This  disappearance correlates to the migration of these hematopoietic stem cells to the foetal liver, where it becomes the subsequent site of haematopoiesis.
• CD40 is also expressed on B cell precursors in the bone marrow, and there is some evidence that CD40-CD154 interactions may play a role in the control of B cell haematopoiesis.
• Notch1 knockouts exhibit normal haematopoiesis in the yolk sac, but fail to produce any HSCs in the AGM . Experiments have been shown that decreased Notch1 expression also affects the expression of Runx1, resulting in its downregulation.
• Other significant work by Bizzozero included research of haematopoiesis in the bone marrow, studies involving phagocytosis in the eye, and the identification of desmosomes ( nodes of Bizzozero ), structures that he first discovered in the stratum spinosum of epidermis.
• FANCA is hypothesised to play a crucial role in adult ( definitive ) haematopoiesis during embryonic development, and is thought to be expressed in all haematopoietic sites that contribute to the formation of haematopoietic stem cells and progenitor cells ( HSPCs ).
• In his research of haematopoiesis, Ferrata helped demonstrate the systemic nature of leukemia, leading him to support an hypothesis that elements of the blood ( erythrocytes, leukocytes, and blood platelets ) all originate from the hemocytoblast, a direct descendant of a mesenchymal cell, which he referred to as an " emoistioblasto " ( hemohistioblast ).
• 2011 : " At the same time, blood stem cells were conceptualized by histologists such as Ernst Neumann and Artur Pappenheim in studies of physiological haematopoiesis and various forms of leukaemia . " " Ernst Neumann pointed to the first successes of Carrel in tissue culturing as a reason for his hope that blood cell cultures might in future be produced as well ( 1912, p . 382 )"