haemosiderin การใช้

• Over time, haemosiderin released from red blood cells trapped in the skin is released causing a brown discolouration of the skin.
• Impaired venous drainage from the foot in varicose veins may sequentially result in brown haemosiderin discolouration to the ankle and foot, varicose stasis dermatitis and finally venous ulcers.
• As they increase, the iron which is initially stored as ferritin is deposited in organs as haemosiderin and this is toxic to tissue, probably at least partially by inducing oxidative stress.